Repairing skeletal muscle - regenerative potential of BFR on skeletal muscle stem cells

Hi there and thanks for tuning in for this month's episode.

Today's topic is actually a request from one of our follower listeners (thanks Dann) who wanted to hear about the role of BFR and muscle stems cells. The topic of muscle stem cells alone is fascinating where stem cells are present in skeletal muscle tissue and they can self-renew and are capable of giving rise to skeletal muscle cells. Stem cells are activated in response to muscle injury to regenerate damaged muscle tissue. So whether we are talking about general or athletic populations, the ability to activate or enhance muscle stem cell response around injury has fantastic implication for recovery.

As it worked out, I had an article in mind. I also try to explain some of the terms used in the paper to make it easy for you all to understand.  I hope you enjoy it as much as I did reviewing it. If you have any other topics of particular interest please comment through my pod bean account, website or social media (@chrisgaviglio).

The paper I review is:

Proliferation of myogenic stem cells in human skeletal muscle in response to low-load resistance training with blood flow restriction.

Nielsen JL¹, Aagaard P, Bech RD, Nygaard T, Hvid LG, Wernbom M, Suetta C, Frandsen U.

 

J Physiol. 2012 Sep 1;590(17):4351-61. doi: 10.1113/jphysiol.2012.237008. Epub 2012 Jul 16.

 

Click this link to access the abstract